Since people are recommending mobo brands, I'm going throw Asus into the ring, I have built 3 machines using their boards and they have been great.
at the draft party a couple of years ago, and under a considerable haze, i heard Birdman yell out the following (about 4 or 5 times, i think) - "don't marry yourselves to players!" he went on to reiterate that idea more than once on the boards, and i believe it to be absolutely sage.
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"If you can accept losing, you can't win."
If you know what motherboard and processor you want, I recommend ordering from a site that does installation and testing of the cpu.
I generally have my CPU installed on the mobo before it gets shipped (costs 9 dollars), which saves me the headache of having to do that myself. I'm kind of a klutz. Sites like www.mwave.com can do that for you.
If you can't handle installing a CPU onto a mobo, then you shouldn't be building your own system.